SCHEMBL2848834

SCHEMBL2848834

CCCCNCCCC.Cn1nnc2c(C(=O)O)cccc21

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.43
CA9 Q16790 3/20 0.43
CYP2C9 P11712 1/20 0.39
HPGD P15428 1/20 0.39
GRM2 Q14416 1/20 0.39
TSHR P16473 1/20 0.38
HTT P42858 1/20 0.38
KDM6B O15054 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
RIPK1 Q13546 1/20 0.37
ASAH1 Q13510 1/20 0.37
GAA P10253 2/20 0.37
CYP4Z1 Q86W10 1/20 0.36
MAPK8 P45983 1/20 0.36
HCAR3 P49019 3/20 0.36
CCKBR P32239 1/20 0.36
NPC1 O15118 1/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2845759 0.95 CA12 (0.43) CA12CA9ASAH1CYP4Z1
SCHEMBL30622603 0.85 HCAR3 (0.45) HPGDGAAHCAR3CCKBRRAB9A
SCHEMBL2012449 0.85 HCAR3 (0.45) HPGDGAAHCAR3CCKBRRAB9A
SCHEMBL2851554 0.83 ALDH1A1 (0.46) CA12CA9GRM2TSHRHTT
Diisopropanolamine SCHEMBL2857245 0.80 CCKBR (0.36) HPGDHCAR3CCKBRRAB9AKDM4E
SCHEMBL28411473 0.79 GRM2 (0.62) GRM2HCAR3
SCHEMBL11490926 0.77 GRM2 (0.56) GRM2HCAR3
SCHEMBL22773113 0.73 KDM4E (0.37) CA12CA9GRM2TSHRGAA
SCHEMBL9819161 0.73 FBP1 (0.49) CYP2C9TSHRHTTCCKBR
SCHEMBL29564879 0.72 GRM2 (0.43) CA12CA9GRM2TSHRGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702567-B2 Moisture curable organopolysiloxane composition and electric/electronic apparatus DOW SILICONES CORPORATION (US) 2023-07-18 US disclosed
US-20230053517-A1 COLORANT FOR HEAT TRANSFER FLUID, AND COMPOSITION COMPRISING SAME KD FINECHEM CO., LTD. (KR) 2023-02-23 US disclosed
EP-3103842-B1 CURABLE SILICONE COMPOSITION, CURED OBJECT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW TORAY CO LTD (JP) 2023-01-11 EP disclosed
EP-3802717-B1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION AND ELECTRIC/ELECTRONIC APPARATUS DOW SILICONES CORP (US) 2022-12-21 EP disclosed
EP-4074781-A1 COLORANT FOR HEAT TRANSFER FLUID, AND COMPOSITION COMPRISING SAME KD Finechem Co., Ltd. (KR) 2022-10-19 EP disclosed
EP-3039079-B1 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DDP SPECIALTY ELECTRONIC MAT US 9 LLC (US) 2022-05-18 EP disclosed
US-20210238444-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION AND ELECTRIC/ELECTRONIC APPARATUS DOW SILICONES CORPORATION 2021-08-05 US disclosed
EP-3802717-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION AND ELECTRIC/ELECTRONIC APPARATUS Dow Silicones Corporation (US) 2021-04-14 EP disclosed
US-20190161699-A1 FUNCTIONAL FLUID COMPOSITIONS KUKDONG R&D CENTER (KR) 2019-05-30 US disclosed
US-20190161700-A1 FUNCTIONAL FLUID COMPOSITIONS KUKDONG R&D CENTER (KR) 2019-05-30 US disclosed
EP-2930213-A1 CURABLE SILICONE COMPOSITION AND OPTICAL SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2015-10-14 EP disclosed
US-20150218417-A1 Curable Silicone Composition And Optical Semiconductor Device DUROPTIX MATERIALS KABUSHIKI KAISHA (JP) 2015-08-06 US disclosed
EP-2892945-A2 CURABLE SILICONE COMPOSITION AND OPTICAL SEMICONDUCTOR DEVICE Dow Corning Toray Co., Ltd. (JP) 2015-07-15 EP disclosed
WO-2014104388-A2 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-07-03 WO disclosed
WO-2014104389-A2 CURABLE SILICONE COMPOSITION, CURED PRODUCT THEREOF, AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-07-03 WO disclosed
WO-2014038727-A2 CURABLE SILICONE COMPOSITION AND OPTICAL SEMICONDUCTOR DEVICE DOW CORNING TORAY CO., LTD. (JP) 2014-03-13 WO disclosed
EP-2159274-B1 BRAKE FLUID CONTAINING TETRAZOLE CHIYODA CHEMICAL CO LTD (JP) 2013-04-17 EP disclosed
US-8357642-B2 Functional fluid CHIYODA CHEMICAL CO., LTD. (JP) 2013-01-22 US disclosed
US-20100137174-A1 FUNCTIONAL FLUID CHIYODA CHEMICAL CO., LTD. (JP) 2010-06-03 US disclosed
EP-2159274-A1 FUNCTIONAL FLUID Chiyoda Chemical Co. Ltd (JP) 2010-03-03 EP disclosed