SCHEMBL28490756

SCHEMBL28490756

CC(=O)Nc1csc(C(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DAO P14920 3/20 0.52
NAPRT Q6XQN6 1/20 0.45
HSD17B10 Q99714 1/20 0.45
LMNA P02545 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.43
ALDH1A1 P00352 3/20 0.42
GAA P10253 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
CTPS1 P17812 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
KMT2A Q03164 2/20 0.40
MAPT P10636 2/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
POLB P06746 1/20 0.40
ALAD P13716 2/20 0.40
KDM4E B2RXH2 1/20 0.40
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9430177 0.86 MAPT (0.50) NAPRTHSD17B10LMNAL3MBTL1ALDH1A1
SCHEMBL12009451 0.81 LMNA (0.41) NAPRTHSD17B10LMNAL3MBTL1ALDH1A1
SCHEMBL6455231 0.80 ALAD (0.59) DAONAPRTHSD17B10LMNAL3MBTL1
SCHEMBL9430873 0.79 GSK3B (0.39) NAPRTHSD17B10LMNAL3MBTL1ALDH1A1
SCHEMBL2995418 0.76 PRKCZ (0.49) HSD17B10LMNAL3MBTL1ALDH1A1GAA
SCHEMBL13919899 0.76 LEF1 (0.52) DAOCTPS1CA12CA1CA9
SCHEMBL16395928 0.74 DAO (0.48) DAOLMNAALDH1A1CTPS1HTT
SCHEMBL10325584 0.72 DAO (0.46) DAOLMNAALDH1A1CTPS1ALAD
SCHEMBL12533659 0.72 CNR1 (0.62) NAPRTHSD17B10LMNAALDH1A1GAA
SCHEMBL29182556 0.70 DAO (0.44) DAOHSD17B10LMNAALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-214225181-U Raman spectrum detection device 上海鑫谱生物科技有限公司 2021-09-17 CN disclosed
CN-113358882-A Spectral analysis method and device 上海鑫谱生物科技有限公司 2021-09-07 CN disclosed
CN-111830006-A Spectral analysis method and device 上海鑫谱生物科技有限公司 2020-10-27 CN disclosed