Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430177 | 0.80 | MAPT (0.50) | LMNAALDH1A1GAATDP1TP53 | |
| SCHEMBL28490756 | 0.79 | DAO (0.52) | LMNAALDH1A1GAATDP1POLB | |
| SCHEMBL12009451 | 0.76 | LMNA (0.41) | LMNAALDH1A1GAATDP1HTT | |
| SCHEMBL2995418 | 0.74 | PRKCZ (0.49) | LMNAALDH1A1GAATDP1TP53 | |
| SCHEMBL15547606 | 0.73 | DAO (0.59) | GSK3BLMNAALDH1A1HTTMAPT | |
| SCHEMBL15282434 | 0.72 | GSK3B (0.68) | GSK3BLMNAALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL939177 | 0.70 | GSK3B (0.46) | GSK3BLMNAALDH1A1GAATDP1 | |
| SCHEMBL22953102 | 0.69 | GSK3B (0.48) | GSK3BLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL2381692 | 0.69 | LMNA (0.46) | LMNAALDH1A1GAATDP1TP53 | |
| SCHEMBL7813005 | 0.68 | GSK3B (0.52) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994029304-A1 | THIENYLTHIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-12-22 | — | — | WO | disclosed |