SCHEMBL2849388

SCHEMBL2849388

CCc1nc(C)c(CCCN)[nH]1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ADORA1 P30542 4/20 0.34
ADORA3 P0DMS8 3/20 0.34
ADORA2A P29274 2/20 0.34
TLR8 Q9NR97 1/20 0.33
HRH1 P35367 1/20 0.32
HRH4 Q9H3N8 1/20 0.32
KDM4E B2RXH2 1/20 0.31
BAZ2A Q9UIF9 1/20 0.31
DDAH1 O94760 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31531712 0.81 ALDH1A1 (0.41)
SCHEMBL9271915 0.81 TP53 (0.35) TP53L3MBTL1ADORA1ADORA3ADORA2A
SCHEMBL3703117 0.80 PDK2 (0.40) TP53L3MBTL1ADORA1ADORA3ADORA2A
SCHEMBL8443897 0.79 HRH4 (0.39) L3MBTL1TLR8HRH1HRH4KDM4E
SCHEMBL6855320 0.78 ADORA1 (0.43) TP53L3MBTL1ADORA1ADORA3ADORA2A
SCHEMBL8444505 0.77 GAA (0.44) KDM4E
SCHEMBL25047048 0.76 L3MBTL1 (0.44) TP53L3MBTL1ADORA1ADORA3ADORA2A
SCHEMBL18824951 0.74 ADORA1 (0.34) ADORA1ADORA3ADORA2AHRH1HRH4
SCHEMBL2418776 0.74 CASP1 (0.39) TP53L3MBTL1ADORA1ADORA3ADORA2A
SCHEMBL83104 0.73 L3MBTL1 (0.34) TP53L3MBTL1ADORA1ADORA3ADORA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0677540-B1 Process for the preparation of polyurethane foams in the presence of amino alkyl or aminophenyl imidazoles as catalysts, as well as the use of these catalysts for the preparation of polyisocyanate-polyaddition products BASF AG (DE) 1999-01-27 EP claimed
WO-2023225151-A1 ACRYLATE-EPOXY RESIN COMPOSITIONS LYONDELLBASELL COMPOSITES LLC (US) 2023-11-23 WO disclosed
EP-3917984-A1 POLYURETHANE AND UV-MOISTURE DUAL CURE PU REACTIVE HOTMELT COMPRISING THE SAME BASF SE (DE) 2021-12-08 EP disclosed
WO-2020156802-A1 POLYURETHANE AND UV-MOISTURE DUAL CURE PU REACTIVE HOTMELT COMPRISING THE SAME BASF SE (DE) 2020-08-06 WO disclosed
US-10350544-B2 Gas treating solutions containing imidazole-amine compounds THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2019-07-16 US disclosed
EP-3349981-A2 LOAD-BEARING COMPOSITE PANELS, MATERIALS, PRODUCTS, AND PROCESSES TO MAKE AND USE SAME Jerez, Roberto Velozzi (US) 2018-07-25 EP disclosed
US-20180021723-A1 GAS TREATING SOLUTIONS CONTAINING IMIDAZOLE-AMINE COMPOUNDS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA 2018-01-25 US disclosed
WO-2017112012-A9 LOAD-BEARING COMPOSITE PANELS, MATERIALS, PRODUCTS, AND PROCESSES TO MAKE AND USE SAME JEREZ ROBERTO VELOZZI (US) 2017-08-10 WO disclosed
WO-2016126957-A1 GAS TREATING SOLUTIONS CONTAINING IMIDAZOLE-AMINE COMPOUNDS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ALABAMA (US) 2016-08-11 WO disclosed
EP-2195229-A2 ROOF MODULE Bayer MaterialScience AG (DE) 2010-06-16 EP disclosed
WO-2009043446-A2 ROOF MODULE BAYER MATERIALSCIENCE AG (DE) 2009-04-09 WO disclosed
WO-2008103669-A1 DOOR STRUCTURES COMPRISING FIBER-REINFORCED COMPOSITES JELD-WEN, INC. (US) 2008-08-28 WO disclosed
EP-1751367-A1 FIBER-REINFORCED COMPOSITES AND BUILDING STRUCTURES COMPRISING FIBER-REINFORCED COMPOSITES Jeld-Wen, Inc. (US) 2007-02-14 EP disclosed
WO-2005106155-A1 FIBER-REINFORCED COMPOSITES AND BUILDING STRUCTURES COMPRISING FIBER-REINFORCED COMPOSITES JELD-WEN, INC. (US) 2005-11-10 WO disclosed
EP-1480804-A1 METHOD FOR CONSTRUCTING COMPOSITE MOULDED PARTS BASF AKTIENGESELLSCHAFT (DE) 2004-12-01 EP disclosed
WO-2003085021-A1 CATALYST SYSTEMS CONTAINING CATALYSTS THAT ARE EMBEDDED IN WAX BASF AKTIENGESELLSCHAFT (DE) 2003-10-16 WO disclosed
WO-2003072334-A1 METHOD FOR CONSTRUCTING COMPOSITE MOULDED PARTS BASF AKTIENGESELLSCHAFT (DE) 2003-09-04 WO disclosed
EP-1335944-A1 CATALYST SYSTEM, CONTAINING CATALYSTS ENCAPSULATED IN WAX BASF AKTIENGESELLSCHAFT (DE) 2003-08-20 EP disclosed
WO-2002031013-A1 CATALYST SYSTEM, CONTAINING CATALYSTS ENCAPSULATED IN WAX BASF AKTIENGESELLSCHAFT (DE) 2002-04-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10350544-B2 Gas treating solutions containing imidazole-amine compounds NISCH, INMT, GMPS TP53 1284/4885L3MBTL1 2240/4885ADORA1 1374/4885
US-20180021723-A1 GAS TREATING SOLUTIONS CONTAINING IMIDAZOLE-AMINE COMPOUNDS NISCH, INMT, GMPS TP53 1284/4885L3MBTL1 2240/4885ADORA1 1374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.