Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.39 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATR | Q13535 | 2/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30304684 | 0.81 | ALDH1A1 (0.40) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL29864329 | 0.74 | ALDH1A1 (0.44) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL29863818 | 0.72 | YTHDC1 (0.42) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL28522883 | 0.68 | PDE9A (0.42) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL26964613 | 0.68 | CYP4F2 (0.44) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL19465657 | 0.68 | CYP4F2 (0.42) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL31111100 | 0.68 | CYP4F2 (0.45) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL30529526 | 0.67 | ALDH1A1 (0.44) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL158414 | 0.67 | CYP4F2 (0.52) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 | |
| SCHEMBL25322203 | 0.67 | ALDH1A1 (0.45) | ALDH1A1LMNAPOLBCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226808-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2021-01-01 | — | — | CN | disclosed |