Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE9A | O76083 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511267 | 0.84 | ALDH1A1 (0.40) | PDE9AALDH1A1LMNAPOLBRXRA | |
| SCHEMBL28512361 | 0.81 | TNKS (0.41) | PDE9AALDH1A1LMNAPOLBRXRA | |
| SCHEMBL29864329 | 0.73 | ALDH1A1 (0.44) | PDE9AALDH1A1LMNAPOLBRXRA | |
| SCHEMBL29863818 | 0.71 | YTHDC1 (0.42) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL28519148 | 0.70 | KDM4E (0.40) | ALDH1A1LMNAPOLBKDM4ERECQL | |
| SCHEMBL7885834 | 0.69 | PDE9A (0.71) | PDE9APDE1C | |
| SCHEMBL7882941 | 0.69 | PDE9A (0.68) | PDE9APDE1C | |
| SCHEMBL28495548 | 0.68 | ALDH1A1 (0.42) | PDE9AALDH1A1LMNAPOLBRXRA | |
| SCHEMBL12465302 | 0.68 | PDE9A (0.70) | PDE9APDE1C | |
| SCHEMBL23013915 | 0.68 | ALDH1A1 (0.44) | PDE9AALDH1A1LMNAPOLBRXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107226807-B | Tankyrase inhibitors | 北京四环制药有限公司 | 2021-01-01 | — | — | CN | disclosed |