Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.53 |
| ▸ | MMP1 | P03956 | 1/20 | 0.52 |
| ▸ | MMP7 | P09237 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | MMP12 | P39900 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6970033 | 0.84 | L3MBTL1 (0.64) | POLBHSD17B10L3MBTL1PKMALDH1A1 | |
| SCHEMBL28498338 | 0.81 | ALDH1A1 (0.65) | POLBHSD17B10ALDH1A1LMNAKMT2A | |
| SCHEMBL5749606 | 0.80 | TAAR1 (0.54) | TAAR1MMP1MMP7MMP8MMP12 | |
| SCHEMBL9153832 | 0.80 | MMP1 (0.59) | TAAR1MMP1MMP7MMP8MMP12 | |
| Homarylamine SCHEMBL29412731 | 0.79 | TAAR1 (0.61) | POLBTAAR1KDM4EPKMTDP1 | |
| Homarylamine SCHEMBL1237889 | 0.79 | TAAR1 (0.61) | POLBTAAR1KDM4EPKMTDP1 | |
| SCHEMBL30496700 | 0.79 | POLB (0.66) | POLBTAAR1KDM4EPKMTDP1 | |
| SCHEMBL28497471 | 0.78 | ALDH1A1 (0.59) | POLBHSD17B10TAAR1KDM4EPKM | |
| Sulfuric Acid SCHEMBL11529866 | 0.78 | TAAR1 (0.55) | POLBHSD17B10TAAR1MMP1MMP7 | |
| SCHEMBL9736670 | 0.76 | POLB (0.59) | POLBTAAR1KDM4EPKMTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112110932-B | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2021-12-28 | — | — | CN | disclosed |
| CN-112110932-A | Method for synthesizing phthalide tetrahydroisoquinoline compound by tandem cyclization strategy | 沈阳药科大学 | 2020-12-22 | — | — | CN | disclosed |