Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30496700 | 0.90 | POLB (0.66) | POLBMEN1KMT2ATAAR1KDM4E | |
| SCHEMBL23389370 | 0.89 | POLB (0.58) | POLBMEN1KMT2ATAAR1KDM4E | |
| SCHEMBL30859493 | 0.89 | POLB (0.58) | POLBMEN1KMT2ATAAR1KDM4E | |
| SCHEMBL108732 | 0.85 | POLB (0.69) | POLBMEN1KMT2ATAAR1KDM4E | |
| SCHEMBL429483 | 0.84 | TAAR1 (0.67) | TAAR1KDM4EALDH1A1TDP1LMNA | |
| SCHEMBL20689715 | 0.83 | POLB (0.59) | POLBMEN1KMT2ATAAR1KDM4E | |
| SCHEMBL12509821 | 0.83 | ALDH1A1 (0.63) | MEN1KMT2AKDM4EALDH1A1 | |
| Homarylamine SCHEMBL29412731 | 0.83 | TAAR1 (0.61) | POLBTAAR1KDM4EALDH1A1TDP1 | |
| Homarylamine SCHEMBL1237889 | 0.83 | TAAR1 (0.61) | POLBTAAR1KDM4EALDH1A1TDP1 | |
| SCHEMBL30614477 | 0.83 | POLB (0.56) | POLBMEN1KMT2ATAAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119923380-A | N-substituted phenylalkylamines and their use as therapeutic agents | 亚历山大舒尔金研究所有限公司 | 2025-05-02 | — | — | CN | disclosed |
| US-12043605-B2 | Deuterated empathogens | ALEXANDER SHULGIN RESEARCH INSTITUTE, INC. (US) | 2024-07-23 | — | — | US | disclosed |
| WO-2023229295-A1 | PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF CANCER COMPRISING PHENYLPROPENE DERIVATIVE AS ACTIVE INGREDIENT | 재단법인 대구경북첨단의료산업진흥재단 | 2023-11-30 | — | — | WO | disclosed |
| WO-2023081897-A1 | ISOTOPICALLY ENRICHED 3,4-METHYLENEDIOXY-N-ETHYLAMPHETAMINE (MDE) AND STEREOISOMERS THEREOF | TERRAN BIOSCIENCES, INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| US-9447081-B2 | Substituted pyrimidines as pharmaceuticals and insecticides | SHENYANG SINOCHEM AGROCHEMICALS R&D CO., LTD. (CN) | 2016-09-20 | — | — | US | disclosed |
| US-20150225378-A1 | HOMOPIPERONY LAMINE COMPOUND AND USE THEREOF | SINOCHEM CORPORATION (CN) | 2015-08-13 | — | — | US | disclosed |
| US-5120759-A | TETRAHYDRONAPHTHALENE DERIVATIVES FOR IMPROVING SHORT-TERM MEMORY | HOFFMANN-LA ROCHE INC. (US) | 1992-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12043605-B2 | Deuterated empathogens | SLC18A2, SLC6A3, GAP43 | POLB 3148/4885MEN1 2182/4885KMT2A 1364/4885 |
| US-20150225378-A1 | HOMOPIPERONY LAMINE COMPOUND AND USE THEREOF | CLPP, LRRK2, MYB | POLB 2222/4885MEN1 59/4885KMT2A 3039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.