SCHEMBL28496604

SCHEMBL28496604

CCCc1cccc([SiH2][SiH3])c1CCC

nearest known ligand 0.32

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
DAO P14920 1/20 0.32
LTB4R Q15722 1/20 0.31
LTB4R2 Q9NPC1 1/20 0.31
ADRA2A P08913 1/20 0.30
ADRA2B P18089 1/20 0.30
ADRA2C P18825 1/20 0.30
GRM5 P41594 1/20 0.30
GABRA1 P14867 2/20 0.30
GABRB2 P47870 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL705069 0.81 GABRA1 (0.34) KDM4EALDH1A1GAAHPGDDAO
SCHEMBL21383287 0.81 KDM4E (0.32) KDM4EALDH1A1GAAHPGDDAO
SCHEMBL3482133 0.81 DAO (0.35) KDM4EALDH1A1GAAHPGDDAO
SCHEMBL704074 0.81 ALDH1A1 (0.32) KDM4EALDH1A1GAAHPGDDAO
SCHEMBL704973 0.81 GRM5 (0.33) KDM4EALDH1A1GAAHPGDDAO
SCHEMBL1452942 0.79 ALDH1A1 (0.41) KDM4EALDH1A1GAAHPGDDAO
SCHEMBL703700 0.74 LTB4R (0.30) LTB4RLTB4R2ADRA2AADRA2BADRA2C
SCHEMBL704058 0.74 LTB4R (0.30) LTB4RLTB4R2
SCHEMBL2966302 0.74 KDM4E (0.35) KDM4EALDH1A1GAAHPGDDAO
SCHEMBL8090798 0.73 GABRA1 (0.46) KDM4EALDH1A1GAAHPGDDAO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112110950-B Preparation method of disilane 杭州师范大学 2023-02-14 CN disclosed
CN-112110950-A Preparation method of disilane 杭州师范大学 2020-12-22 CN disclosed