Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 1/20 | 0.44 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 5/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25680865 | 0.80 | PTGS1 (0.38) | PIK3CBPIK3CDPIK3CAPIK3CGPTGS1 | |
| SCHEMBL18555412 | 0.78 | EDNRA (0.44) | EDNRAPIK3CBPIK3CDPIK3CAPIK3CG | |
| SCHEMBL28493309 | 0.78 | PTGS1 (0.39) | PIK3CBPIK3CDPIK3CAPIK3CGPTGS1 | |
| SCHEMBL28493518 | 0.75 | LMNA (0.57) | PIK3CBPIK3CDPIK3CAPIK3CGPTGS1 | |
| SCHEMBL12256025 | 0.75 | GLO1 (0.48) | EDNRAMETGLO1KDM4EKMT2A | |
| SCHEMBL12018120 | 0.74 | KDM4E (0.60) | EDNRAPOLBKDM4EMEN1KMT2A | |
| SCHEMBL14799076 | 0.74 | P4HTM (0.46) | KDM4EKMT2A | |
| SCHEMBL19650821 | 0.74 | PTK2 (0.42) | PIK3CBPIK3CDPIK3CAPIK3CGPTGS1 | |
| SCHEMBL29955903 | 0.74 | ENPP2 (0.38) | PIK3CBPIK3CDPIK3CAPIK3CGGLO1 | |
| SCHEMBL9949119 | 0.73 | KEAP1 (0.38) | PIK3CBPIK3CDPIK3CAPIK3CGGLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112055713-A | Compounds and compositions for treating diseases associated with APJ receptor activity | 安娜普尔纳生物股份有限公司 | 2020-12-08 | — | — | CN | disclosed |