Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | MDM4 | O15151 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | KIF20A | O95235 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28508740 | 0.88 | TP53 (0.52) | KDM4EHTR7HTR6MDM4TP53 | |
| SCHEMBL28501215 | 0.87 | KDM4E (0.50) | KDM4EL3MBTL1HTR7HTR6ALOX5 | |
| SCHEMBL28904632 | 0.83 | MDM2 (0.60) | HTR7HTR6ALOX5MDM4TP53 | |
| SCHEMBL28506801 | 0.82 | TP53 (0.48) | KDM4EL3MBTL1HTR7HTR6MDM4 | |
| SCHEMBL28503127 | 0.82 | MDM4 (0.48) | KDM4EL3MBTL1HTR7HTR6MDM4 | |
| SCHEMBL28505102 | 0.81 | CYP11B1 (0.49) | HTR7HTR6MDM4TP53MDM2 | |
| SCHEMBL28508702 | 0.81 | MDM4 (0.44) | HTR7HTR6MDM4TP53MDM2 | |
| SCHEMBL28498122 | 0.79 | HTR7 (0.65) | KDM4EL3MBTL1HTR7HTR6ALOX5 | |
| SCHEMBL28497091 | 0.79 | MDM4 (0.46) | HTR7HTR6MDM4TP53MDM2 | |
| SCHEMBL28495988 | 0.79 | HTR1A (0.51) | HTR7HTR6MDM4TP53MDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174937-B | 3- (5-imidazolyl) indole compound and preparation method and application thereof | 南京农业大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-112174937-A | 3- (5-imidazolyl) indole compound and preparation method and application thereof | 南京农业大学 | 2021-01-05 | — | — | CN | disclosed |