Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | MDM4 | O15151 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.46 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28508740 | 0.90 | TP53 (0.52) | TP53MDM4MDM2SMN1; SMN2HTT | |
| SCHEMBL28904632 | 0.89 | MDM2 (0.60) | TP53MDM4MDM2SMN1; SMN2HTT | |
| SCHEMBL28503127 | 0.88 | MDM4 (0.48) | TP53MDM4MDM2SMN1; SMN2HTT | |
| SCHEMBL28495988 | 0.88 | HTR1A (0.51) | TP53MDM4MDM2SMN1; SMN2LMNA | |
| SCHEMBL28505102 | 0.88 | CYP11B1 (0.49) | TP53MDM4MDM2SMN1; SMN2HTT | |
| SCHEMBL28514431 | 0.87 | TP53 (0.52) | TP53MDM4MDM2SMN1; SMN2HTT | |
| SCHEMBL28497091 | 0.85 | MDM4 (0.46) | TP53MDM4MDM2HTR7HTR6 | |
| SCHEMBL28507696 | 0.84 | SMN1; SMN2 (0.48) | TP53MDM4MDM2SMN1; SMN2HTT | |
| SCHEMBL28499278 | 0.82 | KDM4E (0.50) | TP53MDM4MDM2SMN1; SMN2HTT | |
| SCHEMBL28503037 | 0.81 | HTR7 (0.48) | TP53MDM4MDM2SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112174937-B | 3- (5-imidazolyl) indole compound and preparation method and application thereof | 南京农业大学 | 2022-06-03 | — | — | CN | disclosed |
| CN-112174937-A | 3- (5-imidazolyl) indole compound and preparation method and application thereof | 南京农业大学 | 2021-01-05 | — | — | CN | disclosed |