Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 4/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6265796 | 0.77 | TLR8 (0.51) | ALDH1A1KDM4EHSD17B10TSHRNPSR1 | |
| SCHEMBL11622203 | 0.73 | PTGS2 (0.51) | KDM4EHSD17B10NR1H3NR1H2MAPT | |
| SCHEMBL28332981 | 0.71 | PTGS2 (0.43) | ALDH1A1HSD17B10NLRP3NR1H3NR1H2 | |
| SCHEMBL5666175 | 0.71 | P2RX7 (0.46) | ALDH1A1KDM4ENLRP3NR1H3NR1H2 | |
| SCHEMBL5297516 | 0.69 | TLR8 (0.46) | TSHRL3MBTL1ADORA1PDE10ATLR8 | |
| SCHEMBL28490976 | 0.68 | NLRP3 (0.49) | ALDH1A1KDM4EHSD17B10NLRP3TSHR | |
| Hydrochloric Acid SCHEMBL8316038 | 0.67 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EMAPK1L3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL8316036 | 0.67 | SMN1; SMN2 (0.48) | ALDH1A1KDM4EMAPK1L3MBTL1NPC1 | |
| Hydrochloric Acid SCHEMBL8316044 | 0.67 | GABRA2 (0.44) | ALDH1A1KDM4EHSD17B10NR1H3NR1H2 | |
| SCHEMBL12124932 | 0.65 | L3MBTL1 (0.53) | ALDH1A1KDM4EHSD17B10TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110294751-B | Imidazo [4,5-b ] pyridine compound with biological activity and preparation method and application thereof | 湖南化工研究院有限公司 | 2020-11-20 | — | — | CN | disclosed |