Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.32 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18343819 | 0.78 | LMNA (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11806002 | 0.78 | LMNA (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL20145309 | 0.76 | LMNA (0.38) | LMNAKDM4ETDP1CHRNB2CHRNA4 | |
| SCHEMBL16417086 | 0.76 | LMNA (0.39) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL28512964 | 0.75 | KDM4E (0.33) | LMNAKDM4ETDP1ALDH1A1GAA | |
| SCHEMBL8431987 | 0.74 | ALDH1A1 (0.39) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11805305 | 0.73 | DNM1 (0.41) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3894850 | 0.73 | CHRM1 (0.39) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL22035030 | 0.73 | LMNA (0.34) | LMNACHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL608446 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236172-A | Methods and compounds for treating disorders | 福宏治疗公司 | 2021-01-15 | — | — | CN | disclosed |
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |