Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852442 | 0.88 | MALT1 (0.56) | MALT1 | |
| SCHEMBL2850882 | 0.85 | MALT1 (0.44) | MALT1 | |
| SCHEMBL2855927 | 0.84 | MALT1 (0.57) | MALT1 | |
| SCHEMBL2850226 | 0.80 | MALT1 (0.56) | MALT1 | |
| SCHEMBL2850244 | 0.79 | MALT1 (0.51) | MALT1 | |
| SCHEMBL2855566 | 0.76 | MALT1 (0.44) | MALT1 | |
| SCHEMBL2295633 | 0.76 | MAPT (0.60) | MALT1 | |
| SCHEMBL15187958 | 0.75 | KEAP1 (0.50) | MALT1 | |
| SCHEMBL2856635 | 0.74 | MALT1 (0.42) | MALT1 | |
| SCHEMBL2850508 | 0.74 | CCR1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | disclosed |