SCHEMBL28503245

SCHEMBL28503245

CC1=C(c2ccccc2CSCc2ccccc2C2=C(C)C(c3ccccc3)=C(c3ccccc3)C2C)C(C)C(c2ccccc2)=C1c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
LMNA P02545 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PDCD1 Q15116 1/20 0.34
CD274 Q9NZQ7 1/20 0.34
DPP4 P27487 1/20 0.31
MITF O75030 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP2C9 P11712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28504221 0.91 ALDH1A1 (0.33) ALDH1A1LMNATDP1L3MBTL1MITF
SCHEMBL28503247 0.84 PDCD1 (0.35) ALDH1A1PDCD1CD274DPP4MITF
SCHEMBL28494645 0.83 TACR1 (0.38) ALDH1A1PDCD1CD274DPP4MITF
SCHEMBL28506921 0.80 CYP11B1 (0.39) LMNAPDCD1CD274HTT
SCHEMBL28494589 0.80 TACR1 (0.36) ALDH1A1PDCD1CD274MITFMAPT
SCHEMBL9359481 0.78 LMNA (0.33) ALDH1A1LMNAL3MBTL1MAPT
SCHEMBL28495517 0.77 CYP11B1 (0.36) PDCD1CD274
SCHEMBL776889 0.70 DPP4 (0.58) ALDH1A1LMNATDP1L3MBTL1PDCD1
SCHEMBL6569636 0.70 ALDH1A1 (0.40) ALDH1A1LMNATDP1L3MBTL1MITF
SCHEMBL28503244 0.65 LMNA (0.35) ALDH1A1LMNATDP1L3MBTL1PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111620914-B Side-arm metallocene tetravalent transition metal complex containing neutral benzyl heteroatom ligand and application thereof 吉林大学 2021-03-19 CN disclosed
CN-111620914-A Side-arm metallocene tetravalent transition metal complex containing neutral benzyl heteroatom ligand and application thereof 吉林大学 2020-09-04 CN disclosed