Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.32 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6569636 | 0.86 | ALDH1A1 (0.40) | LMNAPDE4BALDH1A1PTGS2L3MBTL1 | |
| SCHEMBL28503247 | 0.79 | PDCD1 (0.35) | ALDH1A1MAPT | |
| SCHEMBL11527348 | 0.79 | PTGS2 (0.33) | PDE4BPTGS2CRHBPCRHR2MAPT | |
| SCHEMBL28494645 | 0.78 | TACR1 (0.38) | PDE4BALDH1A1MAPT | |
| SCHEMBL28503245 | 0.78 | ALDH1A1 (0.34) | LMNAALDH1A1L3MBTL1MAPT | |
| SCHEMBL9250727 | 0.76 | ALDH1A1 (0.35) | LMNAALDH1A1PTGS2CRHBPCRHR2 | |
| SCHEMBL3686925 | 0.76 | ALDH1A1 (0.35) | LMNAALDH1A1PTGS2CRHBPCRHR2 | |
| SCHEMBL31645549 | 0.72 | ALDH1A1 (0.38) | LMNAALDH1A1PTGS2TSHRMAPT | |
| SCHEMBL9978305 | 0.71 | ALDH1A1 (0.35) | LMNAPDE4BALDH1A1CRHBPCRHR2 | |
| SCHEMBL10504794 | 0.69 | LMNA (0.34) | LMNAPDE4BALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0345653-B1 | Transition metal complex | BASF AG (DE) | 1994-10-26 | — | — | EP | disclosed |
| US-5103065-A | TRANSITION METAL COMPLEXES AS CATALYSTS FOR HYDROGENATION HYDROFORMYLATION AND CYCLOTRIMERIZATION | BASF AKTIENGESELLSCHAFT (DE) | 1992-04-07 | — | — | US | disclosed |
| US-4999443-A | Transition metal complexes | BASF AKTIENGESELLSCHAFT (DE) | 1991-03-12 | — | — | US | disclosed |