SCHEMBL28503247

SCHEMBL28503247

CC1=C(c2ccccc2CS)C(C)C(c2ccccc2)=C1c1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
DPP4 P27487 1/20 0.32
MITF O75030 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
FOLH1 Q04609 1/20 0.31
IDO1 P14902 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28494645 0.84 TACR1 (0.38) PDCD1CD274DPP4MITFALDH1A1
SCHEMBL28503245 0.84 ALDH1A1 (0.34) PDCD1CD274DPP4MITFALDH1A1
SCHEMBL28506921 0.81 CYP11B1 (0.39) PDCD1CD274HTT
SCHEMBL28494589 0.81 TACR1 (0.36) PDCD1CD274MITFALDH1A1MAPT
SCHEMBL9359481 0.79 LMNA (0.33) ALDH1A1MAPT
SCHEMBL28495517 0.78 CYP11B1 (0.36) PDCD1CD274
SCHEMBL28504221 0.77 ALDH1A1 (0.33) MITFALDH1A1MAPTHTTNPSR1
SCHEMBL6569636 0.71 ALDH1A1 (0.40) MITFALDH1A1MAPTHTTNPSR1
SCHEMBL2209528 0.69 DPP4 (0.60) PDCD1CD274DPP4ALDH1A1FOLH1
SCHEMBL6701464 0.66 DPP4 (0.50) PDCD1CD274DPP4ALDH1A1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111620914-B Side-arm metallocene tetravalent transition metal complex containing neutral benzyl heteroatom ligand and application thereof 吉林大学 2021-03-19 CN disclosed
CN-111620914-A Side-arm metallocene tetravalent transition metal complex containing neutral benzyl heteroatom ligand and application thereof 吉林大学 2020-09-04 CN disclosed