Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.56 |
| ▸ | PARP1 | P09874 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.52 |
| ▸ | GUSB | P08236 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | QTRT1 | Q9BXR0 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004217 | 0.87 | TNKS2 (0.51) | TNKS2PARP1KDM4CGUSBRAB9A | |
| Hydrochloric Acid SCHEMBL15742407 | 0.86 | KDM4C (0.65) | TNKS2PARP1KDM4EALDH1A1KDM4C | |
| SCHEMBL28502323 | 0.84 | HCAR2 (0.53) | TNKS2PARP1KDM4CGUSBRAB9A | |
| SCHEMBL28503293 | 0.82 | PARP1 (0.59) | TNKS2PARP1ALDH1A1KDM4CGUSB | |
| SCHEMBL17503823 | 0.81 | KDM4C (0.80) | KDM4EKDM4CPDE5A | |
| SCHEMBL6597891 | 0.81 | ACHE (0.48) | TNKS2PARP1KDM4EALDH1A1KDM4C | |
| SCHEMBL6473755 | 0.80 | KDM4C (0.75) | TNKS2PARP1KDM4CGUSBRAB9A | |
| SCHEMBL148952 | 0.79 | TNKS2 (0.61) | TNKS2PARP1KDM4EALDH1A1GUSB | |
| SCHEMBL31070299 | 0.79 | TNKS2 (0.61) | TNKS2PARP1KDM4EALDH1A1GUSB | |
| SCHEMBL38651228 | 0.79 | HTR3A (0.56) | TNKS2PARP1KDM4EALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1484970-A2 | BENZAMIDES AND COMPOSITIONS COMPRISING BENZAMIDES FOR USE AS FUNGICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2004-12-15 | — | — | EP | disclosed |
| WO-2003079788-A2 | BENZAMIDES AND COMPOSITIONS BENZAMIDES FOR USE AS FUNGIZIDE | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-10-02 | — | — | WO | disclosed |