Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2862824 | 0.82 | GAA (0.53) | SMN1; SMN2GAACA1CA2ALDH1A1 | |
| SCHEMBL2850471 | 0.81 | SMN1; SMN2 (0.48) | KDM4ESMN1; SMN2RAB9ANPC1GAA | |
| SCHEMBL2860468 | 0.76 | KDM4E (0.44) | KDM4ETAAR1 | |
| SCHEMBL2850486 | 0.76 | MAPT (0.46) | KDM4ERAB9ANPC1TAAR1GAA | |
| SCHEMBL2854702 | 0.75 | USP2 (0.42) | KDM4ERAB9ANPC1ALDH1A1HTT | |
| SCHEMBL22281950 | 0.73 | SMN1; SMN2 (0.58) | KDM4ESMN1; SMN2RAB9ANPC1TAAR1 | |
| SCHEMBL2852998 | 0.71 | NPC1 (0.59) | KDM4ESMN1; SMN2RAB9ANPC1TAAR1 | |
| SCHEMBL11171119 | 0.69 | KMT2A (0.66) | KDM4ESMN1; SMN2RAB9ANPC1HDAC2 | |
| SCHEMBL4970754 | 0.68 | KDM4E (0.35) | KDM4ESMN1; SMN2ALDH1A1HTT | |
| SCHEMBL27919020 | 0.68 | KDM4E (0.36) | KDM4ESMN1; SMN2RAB9ANPC1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |