Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2850381 | 0.82 | KDM4E (0.43) | GAACA1CA2ALDH1A1SMN1; SMN2 | |
| SCHEMBL2854891 | 0.79 | ABCB1 (0.52) | GAACA1CA2CA12CA9 | |
| SCHEMBL2856544 | 0.78 | ABCB1 (0.53) | GAAALDH1A1CNR1SMN1; SMN2LMNA | |
| SCHEMBL7265002 | 0.77 | CA12 (0.73) | GAACA1CA2CA12CA9 | |
| SCHEMBL2850868 | 0.76 | ALDH1A1 (0.51) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL2857856 | 0.76 | TSHR (0.49) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL6280197 | 0.75 | CA12 (0.56) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL2859179 | 0.75 | ALDH1A1 (0.51) | ALDH1A1MAPK1MAPTLMNAKMT2A | |
| SCHEMBL2850471 | 0.75 | SMN1; SMN2 (0.48) | GAAALDH1A1CNR1MAPK1POLB | |
| SCHEMBL3279938 | 0.74 | ALDH1A1 (0.68) | GAACA1CA2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |