Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2852033 | 0.81 | LMNA (0.52) | USP2NPC1RAB9ALMNATSHR | |
| SCHEMBL2861285 | 0.77 | MAPT (0.46) | USP2PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL2850381 | 0.75 | KDM4E (0.43) | NPC1RAB9ACYP2C9FLT1KDR | |
| SCHEMBL968701 | 0.69 | USP2 (0.51) | USP2LMNATSHRCYP2C9CYP2C19 | |
| SCHEMBL2755872 | 0.69 | USP2 (0.60) | USP2LMNATSHRCYP2C9CYP2C19 | |
| SCHEMBL2856483 | 0.68 | ALDH1A1 (0.45) | LMNACYP2C9CYP2C19MAPTCYP1A2 | |
| SCHEMBL2092776 | 0.68 | USP2 (0.59) | USP2LMNATSHRCYP2C9CYP2C19 | |
| SCHEMBL27919020 | 0.68 | KDM4E (0.36) | USP2NPC1RAB9ATSHRCYP2C19 | |
| SCHEMBL4970754 | 0.68 | KDM4E (0.35) | LMNAMEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL9232485 | 0.67 | KMT2A (0.44) | NPC1RAB9ALMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |