Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2861199 | 0.90 | AOC3 (0.49) | — | |
| SCHEMBL2857889 | 0.87 | NPC1 (0.52) | NPC1LMNASMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL2862872 | 0.83 | CCR1 (0.47) | NPC1CYP3A4KDM4ERAB9AKMT2A | |
| SCHEMBL2854621 | 0.82 | TSHR (0.58) | NPC1LMNASMN1; SMN2RAB9AKMT2A | |
| SCHEMBL2859060 | 0.79 | ALDH1A1 (0.46) | CYP3A4ALDH1A1KDM4E | |
| SCHEMBL2854535 | 0.78 | SMN1; SMN2 (0.60) | POLBNPC1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL2859054 | 0.77 | POLB (0.71) | POLBNPC1LMNAALPLALPI | |
| SCHEMBL7576847 | 0.75 | KMT2A (0.45) | POLBNPC1LMNAALDH1A1KDM4E | |
| SCHEMBL2658763 | 0.75 | ALDH1A1 (0.50) | NPC1LMNASMN1; SMN2ALDH1A1PKM | |
| SCHEMBL9655074 | 0.72 | NPC1 (0.52) | NPC1LMNASMN1; SMN2ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |