Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8785501 | 0.76 | HPGD (0.59) | KMT2ANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL2850762 | 0.75 | POLB (0.47) | KMT2ANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL17976551 | 0.74 | ALDH1A1 (0.44) | RAB9AALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL2857889 | 0.73 | NPC1 (0.52) | KMT2ANPC1RAB9AALDH1A1LMNA | |
| SCHEMBL2658763 | 0.73 | ALDH1A1 (0.50) | KMT2ANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL8177930 | 0.71 | KMT2A (0.71) | KMT2ANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL5703988 | 0.71 | KDM4E (0.41) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL1720197 | 0.70 | NPC1 (0.67) | NPC1RAB9AALDH1A1KDM4EHPGD | |
| SCHEMBL27714667 | 0.70 | KMT2A (0.57) | KMT2ANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL11033378 | 0.69 | HPGD (0.57) | KMT2ANPC1RAB9AALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020035109-A1 | Benzamidine derivatives and their use as anti-coagulants | BERLEX LABORATORIES, INC. | 2002-03-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035109-A1 | Benzamidine derivatives and their use as anti-coagulants | SERPINC1, HABP2, SERPINE1 | KMT2A 1670/4885NPC1 3797/4885RAB9A 2071/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.