Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | GALR3 | O60755 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854621 | 0.80 | TSHR (0.58) | SMN1; SMN2RAB9ANPC1HPGDGALR3 | |
| SCHEMBL2862872 | 0.74 | CCR1 (0.47) | RAB9ANPC1L3MBTL1TSHRMEN1 | |
| SCHEMBL2859060 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HPGDGAA | |
| SCHEMBL9371939 | 0.73 | ALDH1A1 (1.00) | SMN1; SMN2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL7423152 | 0.73 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HTTNPC1HSD17B10 | |
| SCHEMBL2848480 | 0.73 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL30932891 | 0.72 | SMN1; SMN2 (0.75) | SMN1; SMN2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL2937877 | 0.72 | SMN1; SMN2 (0.70) | SMN1; SMN2ALDH1A1HTTRAB9ANPC1 | |
| SCHEMBL2851002 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1HTTRAB9AHPGD | |
| SCHEMBL1709310 | 0.71 | HPGD (0.73) | SMN1; SMN2ALDH1A1RAB9ANPC1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |