Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 3/20 | 0.63 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.58 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.58 |
| ▸ | PLAU | P00749 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | PGR | P06401 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TCF4 | P15884 | 1/20 | 0.51 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20323615 | 0.90 | HTR6 (0.66) | HTR6CYP19A1POLBPIK3C2BPIK3C2G | |
| SCHEMBL15054455 | 0.88 | CYP19A1 (0.80) | HTR6CYP19A1POLBPLAUALDH1A1 | |
| SCHEMBL28509432 | 0.84 | HTR6 (0.75) | HTR6CYP19A1POLBALDH1A1LMNA | |
| SCHEMBL28271796 | 0.82 | HTR6 (0.83) | HTR6CYP19A1POLBALDH1A1LMNA | |
| SCHEMBL28270292 | 0.81 | HTR6 (0.71) | HTR6CYP19A1POLBALDH1A1LMNA | |
| SCHEMBL4072331 | 0.81 | PGR (0.72) | CYP19A1POLBPIK3C2BPIK3C2GPLAU | |
| SCHEMBL22584911 | 0.80 | LMNA (0.73) | HTR6POLBALDH1A1LMNAPKM | |
| SCHEMBL2242644 | 0.79 | HTR6 (0.72) | HTR6CYP19A1POLBALDH1A1LMNA | |
| SCHEMBL28510864 | 0.78 | ALPL (0.64) | HTR6CYP19A1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2723618 | 0.78 | HTR6 (1.00) | HTR6POLBALDH1A1LMNAPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109081793-B | Sulfonamide urease inhibitor and preparation method and application thereof | 吉首大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-109096156-B | Disulfonyl meta-aryl diamine urease inhibitor and preparation method and application thereof | 吉首大学 | 2021-01-15 | — | — | CN | disclosed |