Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.80 |
| ▸ | HTR6 | P50406 | 3/20 | 0.72 |
| ▸ | TCF4 | P15884 | 1/20 | 0.65 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PLAU | P00749 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | PGR | P06401 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28511978 | 0.88 | HTR6 (0.63) | CYP19A1HTR6TCF4CTNNB1ALDH1A1 | |
| SCHEMBL20323615 | 0.87 | HTR6 (0.66) | CYP19A1HTR6ALDH1A1LMNAPKM | |
| SCHEMBL4072331 | 0.87 | PGR (0.72) | CYP19A1ALDH1A1LMNAPKMPLAU | |
| SCHEMBL8711296 | 0.86 | CYP19A1 (0.88) | CYP19A1TCF4CTNNB1ALDH1A1LMNA | |
| SCHEMBL2242644 | 0.85 | HTR6 (0.72) | CYP19A1HTR6TCF4CTNNB1ALDH1A1 | |
| SCHEMBL28271812 | 0.84 | HTR6 (1.00) | CYP19A1HTR6PKMPOLBHTT | |
| SCHEMBL7386463 | 0.84 | CYP19A1 (0.82) | CYP19A1TCF4CTNNB1ALDH1A1LMNA | |
| SCHEMBL9763115 | 0.83 | HTR6 (0.79) | CYP19A1HTR6TCF4CTNNB1ALDH1A1 | |
| SCHEMBL30737507 | 0.83 | HTR6 (0.79) | CYP19A1HTR6TCF4CTNNB1ALDH1A1 | |
| SCHEMBL22584911 | 0.83 | LMNA (0.73) | HTR6ALDH1A1LMNAPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109081793-B | Sulfonamide urease inhibitor and preparation method and application thereof | 吉首大学 | 2021-03-30 | — | — | CN | disclosed |
| WO-2013096151-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2013-06-27 | — | — | WO | disclosed |