Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11983635 | 0.79 | KDM4E (0.75) | KDM4EALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL30343301 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL11455551 | 0.78 | KDM4E (0.63) | KDM4EALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL9650199 | 0.78 | KDM4E (0.65) | KDM4EALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL13587967 | 0.78 | LMNA (0.57) | KDM4EALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL31439711 | 0.78 | ALDH1A1 (0.64) | KDM4EALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL27799043 | 0.77 | KDM4E (0.61) | KDM4EALDH1A1HSD17B10LMNAMEN1 | |
| SCHEMBL17580969 | 0.77 | KDM4E (0.73) | KDM4EALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL502049 | 0.76 | SMN1; SMN2 (0.66) | LMNATSHRHTTTDP1MEN1 | |
| SCHEMBL31439691 | 0.76 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107973755-B | Preparation method of 3-acetamido quinoxalinone derivative | 滨州学院 | 2020-12-29 | — | — | CN | disclosed |