Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | MMP9 | P14780 | 4/20 | 0.46 |
| ▸ | MMP8 | P22894 | 4/20 | 0.46 |
| ▸ | MMP13 | P45452 | 4/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19149792 | 0.75 | APP (0.62) | NPC1RAB9AMEN1POLBMAPT | |
| SCHEMBL12489677 | 0.73 | MAPT (0.85) | NPC1RAB9AMEN1POLBMAPT | |
| SCHEMBL31592008 | 0.73 | APP (0.66) | NPC1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL2461783 | 0.73 | APP (0.66) | NPC1RAB9AMEN1MAPTKMT2A | |
| SCHEMBL25028059 | 0.72 | MMP2 (0.53) | MEN1MAPTKMT2AMMP2MMP9 | |
| SCHEMBL28520867 | 0.71 | RAB9A (0.45) | NPC1RAB9AMEN1POLBMAPT | |
| SCHEMBL19148562 | 0.70 | APP (0.54) | RAB9APOLBMMP2MMP9MMP8 | |
| SCHEMBL19149456 | 0.70 | ILK (0.46) | NPC1RAB9AMEN1KMT2AMMP2 | |
| SCHEMBL7545039 | 0.70 | NPC1 (0.56) | NPC1RAB9AMAPTKMT2A | |
| SCHEMBL28519330 | 0.69 | TSHR (0.47) | NPC1RAB9AMEN1POLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530438-B | Benzothiazole-oxazole alpha-glucosidase inhibitor and preparation method and application thereof | 贵州医科大学 | 2020-12-29 | — | — | CN | disclosed |