Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATF4 | P18848 | 6/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | CCR3 | P51677 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28676495 | 0.94 | ATF4 (0.54) | ATF4KDM4ESMN1; SMN2ALDH1A1HTR1A | |
| SCHEMBL28619817 | 0.84 | SIGMAR1 (0.62) | HTR1ADRD2DRD1DRD5HTR2A | |
| SCHEMBL28588174 | 0.84 | ATF4 (0.57) | ATF4HRH3 | |
| SCHEMBL24225679 | 0.83 | ATF4 (0.57) | ATF4KDM4ESMN1; SMN2ALDH1A1HTR1A | |
| SCHEMBL28906765 | 0.82 | ATF4 (0.61) | ATF4HTR1AHRH1CCR3HTR7 | |
| SCHEMBL28906768 | 0.81 | ATF4 (0.60) | ATF4SMN1; SMN2HTR1APOLB | |
| Trifluoroacetic Acid SCHEMBL21050217 | 0.81 | ATF4 (0.57) | ATF4KDM4ESMN1; SMN2ALDH1A1HRH1 | |
| SCHEMBL21050128 | 0.80 | ATF4 (0.61) | ATF4KDM4ESMN1; SMN2ALDH1A1HRH3 | |
| SCHEMBL5709501 | 0.79 | LTA4H (0.55) | SMN1; SMN2HTR1ADRD2DRD1DRD5 | |
| SCHEMBL28587516 | 0.79 | ATF4 (0.72) | ATF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111757739-A | Integrated stress pathway inhibitors | 普拉西斯生物技术有限责任公司 | 2020-10-09 | — | — | CN | disclosed |