Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.30 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8865254 | 0.69 | OPRM1 (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL6689884 | 0.68 | KDM1A (0.39) | HTR2AHTR2CHTR2BHRH3GRIN2D | |
| SCHEMBL5827252 | 0.68 | ADRA1A (0.44) | KMT2A | |
| SCHEMBL6250927 | 0.67 | ADRA1A (0.54) | KMT2A | |
| Hydrochloric Acid SCHEMBL8614363 | 0.66 | ADRA1A (0.43) | KMT2A | |
| Hydrochloric Acid SCHEMBL8690420 | 0.66 | KDM1A (0.50) | HTR2AHTR2CHTR2BHRH3 | |
| SCHEMBL28513726 | 0.66 | OPRM1 (0.36) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL28478349 | 0.66 | OPRM1 (0.36) | MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL28508991 | 0.65 | OPRM1 (0.35) | MAPK1KMT2A | |
| SCHEMBL769063 | 0.64 | ADRA1A (0.55) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0618906-A1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | ANTII SAKARI HAAPALINNA (FI) | 1994-10-12 | — | — | EP | disclosed |
| WO-1993013074-A1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Orion-Yhtymä Oy (FI) | 1993-07-08 | — | — | WO | disclosed |