Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 5/20 | 0.58 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.57 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.57 |
| ▸ | MGAM | O43451 | 5/20 | 0.55 |
| ▸ | AMY1A | P0DUB6 | 5/20 | 0.55 |
| ▸ | GAA | P10253 | 5/20 | 0.55 |
| ▸ | SI | P14410 | 5/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 5/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.54 |
| ▸ | APAF1 | O14727 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9340128 | 0.87 | SLC9A1 (0.59) | SLC9A1KCNMA1EGLN3MGAMAMY1A | |
| SCHEMBL27267338 | 0.84 | SLC9A1 (0.61) | SLC9A1EGLN3MGAMAMY1AGAA | |
| SCHEMBL3460030 | 0.83 | EGLN3 (0.62) | SLC9A1KCNMA1EGLN3MGAMAMY1A | |
| SCHEMBL13604204 | 0.81 | SLC9A1 (0.55) | SLC9A1EGLN3MGAMAMY1AGAA | |
| SCHEMBL25973425 | 0.80 | SLC9A1 (0.65) | SLC9A1KCNMA1EGLN3MGAMAMY1A | |
| SCHEMBL4346795 | 0.79 | SLC9A1 (0.63) | SLC9A1KCNMA1EGLN3MGAMAMY1A | |
| SCHEMBL6736070 | 0.77 | SLC9A1 (0.66) | SLC9A1KCNMA1EGLN3MGAMAMY1A | |
| SCHEMBL260406 | 0.77 | SLC9A1 (0.66) | SLC9A1KCNMA1EGLN3MGAMAMY1A | |
| Sulfuric Acid SCHEMBL31557704 | 0.77 | SLC9A1 (0.83) | SLC9A1EGLN3RAB9AMAPTNPC1 | |
| SCHEMBL28514074 | 0.77 | GRM2 (0.65) | SLC9A1KCNMA1EGLN3GRM2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-100543124-C | Substrate is with clean-out system and purging method | WAKO PURE CHEM IND LTD (JP) | 2009-09-23 | — | — | CN | claimed |
| EP-2543670-B1 | PYRAZOLOPYRIMIDIN-DERIVATIVE FÜR DIE BEHANDLUNG VON HAUTKRANKHEITEN | KYOWA HAKKO KIRIN CO LTD (JP) | 2016-05-04 | — | — | EP | disclosed |
| EP-2206714-B1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | KYOWA HAKKO KIRIN CO LTD (JP) | 2015-01-21 | — | — | EP | disclosed |
| EP-2781216-A1 | CHEMOKINE RECEPTOR ACTIVITY REGULATOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2014-09-24 | — | — | EP | disclosed |
| US-8815874-B2 | Pyrazolopyrimidine derivative | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-20140221340-A1 | CHEMOKINE RECEPTOR ACTIVITY REGULATOR | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-08-07 | — | — | US | disclosed |
| US-8729264-B2 | Agent for prevention and/or treatment of skin diseases | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2014-05-20 | — | — | US | disclosed |
| US-20130102620-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2013-04-25 | — | — | US | disclosed |
| EP-2543670-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | Kyowa Hakko Kirin Co., Ltd. (JP) | 2013-01-09 | — | — | EP | disclosed |
| US-20100256134-A1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | KYOWA HAKKO KIRIN CO., LTD. (JP) | 2010-10-07 | — | — | US | disclosed |
| EP-2206714-A1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2010-07-14 | — | — | EP | disclosed |
| CN-100543124-C | Substrate is with clean-out system and purging method | WAKO PURE CHEM IND LTD (JP) | 2009-09-23 | — | — | CN | disclosed |
| CN-1875090-A | Cleaning agent for substrate and cleaning method | WAKO PURE CHEM IND LTD (JP) | 2006-12-06 | — | — | CN | disclosed |
| US-20050256166-A1 | Nitrogen-containing compounds | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-11-17 | — | — | US | disclosed |
| EP-1535906-A1 | NITROGEN-CONTAINING COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-01 | — | — | EP | disclosed |
| US-20040063936-A1 | Pyrimidine derivatives and process for preparing the same | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-04-01 | — | — | US | disclosed |
| EP-1346985-A1 | PYRIMIDINE DERIVATIVES AND PROCESS FOR PREPARING THE SAME | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-09-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050256166-A1 | Nitrogen-containing compounds | DPP4, DPP3, DPP8 | SLC9A1 932/4885KCNMA1 3662/4885EGLN3 261/4885 |
| US-20140221340-A1 | CHEMOKINE RECEPTOR ACTIVITY REGULATOR | CXCR2, ACKR3, CCR2 | SLC9A1 1742/4885KCNMA1 3334/4885EGLN3 1386/4885 |
| US-20130102620-A1 | PYRAZOLOPYRIMIDINE DERIVATIVE | GRK3, NR3C2, NR1I3 | SLC9A1 1253/4885KCNMA1 1090/4885EGLN3 1730/4885 |
| US-20040063936-A1 | Pyrimidine derivatives and process for preparing the same | DPYD, NUDT1, UMPS | SLC9A1 768/4885KCNMA1 2684/4885EGLN3 4296/4885 |
| US-20100256134-A1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | TYR, CUTA, SERPINB1 | SLC9A1 118/4885KCNMA1 1545/4885EGLN3 2642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.