Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.40 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | RAB9A | P51151 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679369 | 0.86 | LMNA (0.38) | APOBEC3GEHMT2EHMT1LMNAALDH1A1 | |
| SCHEMBL5133715 | 0.85 | LMNA (0.36) | APOBEC3GEHMT2EHMT1LMNAALDH1A1 | |
| SCHEMBL28514925 | 0.83 | LMNA (0.45) | APOBEC3GEHMT2EHMT1LMNAALDH1A1 | |
| SCHEMBL465750 | 0.81 | LMNA (0.37) | APOBEC3GEHMT2EHMT1LMNAALDH1A1 | |
| SCHEMBL12092095 | 0.81 | LMNA (0.42) | APOBEC3GEHMT2EHMT1LMNAALDH1A1 | |
| SCHEMBL29352062 | 0.79 | ALDH1A1 (0.44) | APOBEC3GEHMT2EHMT1LMNAALDH1A1 | |
| SCHEMBL42368 | 0.79 | ALDH1A1 (0.44) | APOBEC3GEHMT2EHMT1LMNAALDH1A1 | |
| SCHEMBL43414 | 0.78 | POLB (0.41) | APOBEC3GEHMT2EHMT1LMNAALDH1A1 | |
| SCHEMBL278281 | 0.78 | LMNA (0.39) | LMNAALDH1A1SMN1; SMN2RAB9AKMT2A | |
| SCHEMBL5502675 | 0.77 | LMNA (0.36) | APOBEC3GEHMT2EHMT1LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136769-A1 | PEPTIDE DRUG CONJUGATES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-10 | — | — | WO | disclosed |
| WO-2017136769-A1 | PEPTIDE DRUG CONJUGATES | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2017-08-10 | — | — | WO | disclosed |