Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9908238 | 0.80 | TDP1 (0.46) | HTR3EHTR3BCHRM4CHRM5CHRNB2 | |
| SCHEMBL30236919 | 0.77 | HTR3E (0.41) | HTR3EHTR3BCHRM4CHRM5CHRNB2 | |
| SCHEMBL29004397 | 0.70 | TAAR1 (0.40) | L3MBTL1ANPEPATMMEN1LMNA | |
| SCHEMBL13813004 | 0.69 | PLK1 (0.41) | HTR3EHTR3BCHRM4CHRM5CHRNB2 | |
| SCHEMBL15325740 | 0.68 | ANPEP (0.49) | SIGMAR1L3MBTL1ALDH1A1MAPTANPEP | |
| SCHEMBL1188008 | 0.67 | L3MBTL1 (0.42) | HTR3EHTR3BCHRM4CHRM5CHRNB2 | |
| SCHEMBL3671512 | 0.67 | IDO1 (0.49) | HTR3EHTR3BCHRM4CHRM5CHRNB2 | |
| SCHEMBL1983999 | 0.67 | LMNA (0.47) | L3MBTL1ALDH1A1ANPEPHTTRAB9A | |
| SCHEMBL29430352 | 0.67 | LMNA (0.47) | L3MBTL1ALDH1A1ANPEPHTTRAB9A | |
| SCHEMBL3381057 | 0.67 | LMNA (0.47) | L3MBTL1ALDH1A1ANPEPHTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112121463-B | Preparation method of polysubstituted benzo nitrogen-containing heterocyclic methylamine | 烟台宁远药业有限公司 | 2022-03-22 | — | — | CN | claimed |
| CN-112121463-A | Preparation method of polysubstituted benzo nitrogen-containing heterocyclic methylamine | 烟台宁远药业有限公司 | 2020-12-25 | — | — | CN | claimed |
| CN-112028828-A | Preparation method of polysubstituted bromomethylbenzene nitrogen-containing heterocyclic compound | 烟台宁远药业有限公司 | 2020-12-04 | — | — | CN | claimed |
| CN-112028828-B | Preparation method of polysubstituted bromomethylbenzene nitrogen-containing heterocyclic compound | 烟台宁远药业有限公司 | 2023-04-14 | — | — | CN | disclosed |
| CN-112121463-B | Preparation method of polysubstituted benzo nitrogen-containing heterocyclic methylamine | 烟台宁远药业有限公司 | 2022-03-22 | — | — | CN | disclosed |
| CN-112121463-A | Preparation method of polysubstituted benzo nitrogen-containing heterocyclic methylamine | 烟台宁远药业有限公司 | 2020-12-25 | — | — | CN | disclosed |
| CN-112028828-A | Preparation method of polysubstituted bromomethylbenzene nitrogen-containing heterocyclic compound | 烟台宁远药业有限公司 | 2020-12-04 | — | — | CN | disclosed |