Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.45 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.41 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9533937 | 0.77 | ALDH1A1 (0.50) | MAPTTP53ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL15951003 | 0.73 | GABRA5 (0.45) | RAB9AMAPTCACNA1FABCB1CACNA1D | |
| SCHEMBL9903838 | 0.72 | NPSR1 (0.48) | RAB9AMAPTCACNA1FABCB1CACNA1D | |
| SCHEMBL5242546 | 0.72 | KMT2A (0.56) | HTTSMN1; SMN2KMT2AMEN1PTGS2 | |
| SCHEMBL1246411 | 0.72 | KMT2A (0.56) | RAB9AALDH1A1HTTSMN1; SMN2KMT2A | |
| SCHEMBL2470754 | 0.72 | RAB9A (0.54) | RAB9AMAPTCACNA1FABCB1CACNA1D | |
| SCHEMBL9533383 | 0.71 | GPBAR1 (0.51) | MAPTNPC1KMT2AMEN1POLB | |
| SCHEMBL27495331 | 0.71 | KMT2A (0.55) | ALDH1A1HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL8594811 | 0.71 | ALDH1A1 (0.35) | MAPTALDH1A1HTTSMN1; SMN2KDM4E | |
| SCHEMBL9535701 | 0.70 | KMT2A (0.54) | HTTSMN1; SMN2KMT2AMEN1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041316-B | Isoxazole O-linked carbamoyl cyclohexyl acids as LPA antagonists | 百时美施贵宝公司 | 2024-11-22 | — | — | CN | disclosed |
| CN-112041316-A | Isoxazole O-linked carbamoylcyclohexanoic acids as LPA antagonists | 百时美施贵宝公司 | 2020-12-04 | — | — | CN | disclosed |