Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | DDX3X | O00571 | 1/20 | 0.40 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30737550 | 0.89 | HTR6 (0.62) | HTR6MEN1KMT2APOLBPKM | |
| SCHEMBL28270346 | 0.89 | HTR6 (0.62) | HTR6MEN1KMT2APOLBPKM | |
| SCHEMBL28506098 | 0.83 | HTR6 (0.61) | HTR6MEN1KMT2APOLBPKM | |
| SCHEMBL9577174 | 0.82 | POLB (0.54) | MEN1KMT2APOLBPKMCA1 | |
| SCHEMBL28506249 | 0.81 | KMT2A (0.57) | HTR6MEN1KMT2APOLBPKM | |
| SCHEMBL28513727 | 0.81 | HTR6 (0.55) | HTR6MEN1KMT2APOLBPKM | |
| SCHEMBL28270335 | 0.80 | HTR6 (0.66) | HTR6MEN1KMT2APOLBPKM | |
| SCHEMBL9577222 | 0.78 | FABP4 (0.51) | HTR6MEN1KMT2ACA1CA2 | |
| SCHEMBL30737485 | 0.77 | HTR6 (0.62) | HTR6MEN1KMT2APOLBPKM | |
| SCHEMBL30737482 | 0.77 | MEN1 (0.65) | HTR6MEN1KMT2APOLBPTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109081793-B | Sulfonamide urease inhibitor and preparation method and application thereof | 吉首大学 | 2021-03-30 | — | — | CN | disclosed |
| CN-109096156-B | Disulfonyl meta-aryl diamine urease inhibitor and preparation method and application thereof | 吉首大学 | 2021-01-15 | — | — | CN | disclosed |