Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | IL1RN | P18510 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.49 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.49 |
| ▸ | CASP6 | P55212 | 1/20 | 0.49 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | FABP4 | P15090 | 1/20 | 0.46 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.45 |
| ▸ | PGR | P06401 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2741008 | 0.87 | POLB (0.67) | POLBIL1RNKEAP1ERAP1PTPN5 | |
| SCHEMBL9577237 | 0.86 | KEAP1 (0.50) | POLBIL1RNKEAP1ERAP1PTPN5 | |
| SCHEMBL28517047 | 0.82 | HTR6 (0.56) | POLBPTPN5KMT2AMEN1PKM | |
| SCHEMBL7627388 | 0.80 | KEAP1 (0.67) | POLBIL1RNKEAP1ERAP1PTPN5 | |
| SCHEMBL11179607 | 0.80 | TSHR (0.54) | POLBKMT2AMEN1ALDH1A1FABP4 | |
| SCHEMBL9577158 | 0.79 | POLB (0.45) | POLBIL1RNKEAP1ERAP1PTPN5 | |
| SCHEMBL9577222 | 0.77 | FABP4 (0.51) | KMT2AMEN1ALDH1A1FABP4FABP5 | |
| SCHEMBL21914643 | 0.77 | TSHR (0.61) | IL1RNKEAP1ERAP1PTPN5DUSP3 | |
| SCHEMBL28750136 | 0.76 | POLB (0.63) | POLBPTPN5KMT2AMEN1PKM | |
| SCHEMBL9577127 | 0.76 | RECQL (0.58) | KEAP1KMT2AMEN1ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5264474-A | Plasticizing thermoplastic or thermosetting resins with sulfonamide compounds | MTM AMERICAS INC. (US) | 1993-11-23 | — | — | US | disclosed |
| US-4957957-A | Polymer compositions containing aromatic sulfonamide | ETHYL CORPORATION (US) | 1990-09-18 | — | — | US | disclosed |