Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.40 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | DBH | P09172 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.35 |
| ▸ | TUBB | P07437 | 1/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28523893 | 0.85 | SIGMAR1 (0.43) | SIGMAR1HSP90AA1HSP90AB1KCNH2 | |
| SCHEMBL21491970 | 0.78 | CYP19A1 (0.41) | CACNA1HCACNA1GCACNA1IDBHHSP90AA1 | |
| SCHEMBL19611853 | 0.77 | MEN1 (0.56) | HSP90AA1HSP90AB1HDAC1MEN1KMT2A | |
| SCHEMBL28080410 | 0.75 | SIGMAR1 (0.56) | SIGMAR1HDAC1KCNH2 | |
| Hydrochloric Acid SCHEMBL28523889 | 0.74 | TAS2R8 (0.42) | CACNA1HCACNA1GCACNA1IDBHKCNH2 | |
| SCHEMBL28525714 | 0.72 | CACNA1H (0.40) | CACNA1HCACNA1GCACNA1IDBH | |
| SCHEMBL27971447 | 0.71 | SIGMAR1 (0.59) | SIGMAR1NPC1RAB9A | |
| SCHEMBL9369847 | 0.71 | CA5A (0.54) | SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL21492020 | 0.67 | DBH (0.40) | CACNA1HCACNA1GCACNA1IDBHKCNH2 | |
| SCHEMBL17316286 | 0.66 | L3MBTL1 (0.55) | CACNA1HCACNA1GCACNA1IDBHMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |
| CN-112218865-A | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2021-01-12 | — | — | CN | disclosed |