Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 6/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.36 |
| ▸ | RXRA | P19793 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 2/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28526559 | 0.90 | ABCB1 (0.40) | RIPK1ABCB1GPR119NR1H2NR1H3 | |
| SCHEMBL20835496 | 0.89 | CALCRL (0.37) | RIPK1ABCB1KDM1A | |
| SCHEMBL28523788 | 0.80 | ABCB1 (0.46) | RIPK1ABCB1GPR119NR1H2NR1H3 | |
| SCHEMBL28529935 | 0.79 | PKM (0.40) | RIPK1GPR119NR1H2NR1H3RXRA | |
| SCHEMBL20835514 | 0.79 | ABCB1 (0.40) | RIPK1ABCB1GPR119NR1H2NR1H3 | |
| SCHEMBL20835760 | 0.78 | CALCRL (0.38) | RIPK1ABCB1KDM1A | |
| SCHEMBL16004572 | 0.78 | RORC (0.44) | RIPK1ABCB1GPR119NR1H2NR1H3 | |
| SCHEMBL28285321 | 0.76 | GPR119 (0.43) | RIPK1ABCB1GPR119NR1H2NR1H3 | |
| SCHEMBL5152764 | 0.76 | GPR119 (0.44) | RIPK1ABCB1GPR119NR1H2NR1H3 | |
| SCHEMBL20835558 | 0.75 | ABCB1 (0.38) | RIPK1ABCB1GPR119NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |