Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857628 | 0.91 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2KMT2ALMNA | |
| SCHEMBL2855547 | 0.87 | TAAR1 (0.54) | TAAR1GLAP2RX7NPC1RAB9A | |
| SCHEMBL2853253 | 0.86 | KEAP1 (0.42) | LMNAL3MBTL1HPGD | |
| SCHEMBL2859861 | 0.85 | TAAR1 (0.51) | TAAR1GLASMN1; SMN2KMT2ALMNA | |
| SCHEMBL2852221 | 0.84 | ALDH1A1 (0.46) | TAAR1GLANPC1RAB9AGAA | |
| SCHEMBL2856467 | 0.84 | P2RX7 (0.51) | GLAP2RX7NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL2852539 | 0.84 | LMNA (0.52) | GAAKMT2ALMNAMEN1TDP1 | |
| SCHEMBL2854509 | 0.83 | KDM4E (0.50) | TAAR1GLANPC1RAB9AGAA | |
| SCHEMBL2856260 | 0.83 | TSHR (0.46) | SMN1; SMN2LMNACNR1HPGD | |
| SCHEMBL2855603 | 0.82 | P2RX1 (0.44) | P2RX7GAALMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |