Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CCR1 | P32246 | 6/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | PADI3 | Q9ULW8 | 1/20 | 0.38 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2857628 | 0.93 | NPC1 (0.40) | LMNAHPGDCCR1 | |
| SCHEMBL2852539 | 0.90 | LMNA (0.52) | LMNAHPGDCCR1PLA2G1BATG4B | |
| SCHEMBL2856294 | 0.89 | CCR1 (0.49) | KEAP1NFE2L2EPHX1CCR1LIPG | |
| SCHEMBL2856260 | 0.87 | TSHR (0.46) | LMNAHPGDCCR1 | |
| SCHEMBL2851930 | 0.86 | TAAR1 (0.47) | LMNAHPGDL3MBTL1 | |
| SCHEMBL2856304 | 0.85 | KEAP1 (0.53) | KEAP1NFE2L2EPHX1HPGDCCR1 | |
| SCHEMBL2855603 | 0.85 | P2RX1 (0.44) | LMNAHPGDCCR1 | |
| SCHEMBL2859076 | 0.83 | KEAP1 (0.42) | KEAP1NFE2L2EPHX1CCR1LIPG | |
| SCHEMBL2854462 | 0.82 | KEAP1 (0.48) | KEAP1NFE2L2EPHX1LMNACCR1 | |
| SCHEMBL2859089 | 0.82 | ATG4B (0.43) | KEAP1NFE2L2EPHX1CCR1PADI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |