Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.47 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | NQO2 | P16083 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15780725 | 0.80 | CRHBP (0.49) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL8687444 | 0.79 | ACHE (0.53) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL29359446 | 0.78 | CRHBP (0.61) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL51330 | 0.78 | CRHBP (0.61) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL11532423 | 0.73 | MEN1 (0.50) | CRHBPCRHR2KEAP1NFE2L2RAB9A | |
| SCHEMBL10865681 | 0.73 | ALDH1A1 (0.58) | CRHBPCRHR2KEAP1NFE2L2RAB9A | |
| SCHEMBL30380175 | 0.72 | CRHBP (0.47) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL28425031 | 0.71 | POLB (0.45) | CRHBPCRHR2KEAP1NFE2L2RAB9A | |
| SCHEMBL28532290 | 0.71 | CRHBP (0.64) | CRHBPCRHR2KEAP1NFE2L2ATM | |
| SCHEMBL20475325 | 0.71 | RAB9A (0.53) | RAB9ANPC1MEN1HCRTR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107915687-B | High-efficiency preparation method of polysubstituted phenazine derivative and oxide thereof | 清华大学 | 2021-02-26 | — | — | CN | disclosed |