Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PLK1 | P53350 | 8/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.48 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.47 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.47 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL250247 | 0.83 | HDAC6 (0.80) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL28504926 | 0.78 | LMNA (0.47) | HPGDHTTSMN1; SMN2 | |
| SCHEMBL30080293 | 0.77 | ALDH1A1 (0.52) | HPGDHTT | |
| SCHEMBL20010800 | 0.77 | CES2 (0.52) | HPGD | |
| SCHEMBL14115137 | 0.77 | HDAC6 (0.70) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL16198923 | 0.77 | HDAC6 (0.70) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL27291167 | 0.76 | HDAC6 (0.52) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL23933223 | 0.75 | HDAC8 (0.67) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL2643668 | 0.75 | HDAC8 (0.67) | HDAC6HDAC8HDAC2HPGDTSHR | |
| SCHEMBL159659 | 0.75 | HDAC2 (0.67) | HDAC6HDAC8HDAC2HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112094288-B | Selective catalytic synthesis of aryl silicon amide compounds by ferric salt/isopropyl magnesium chloride and preparation method thereof | 西北工业大学 | 2022-07-26 | — | — | CN | disclosed |
| CN-112094288-A | Selective catalytic synthesis of aryl silicon amide compounds by ferric salt/isopropyl magnesium chloride and preparation method thereof | 西北工业大学 | 2020-12-18 | — | — | CN | disclosed |