Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 11/20 | 0.43 |
| ▸ | MAPT | P10636 | 11/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.41 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.40 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28908255 | 0.86 | MRGPRX4 (0.41) | MAPTALDH1A1MEN1KMT2APOLB | |
| SCHEMBL28521420 | 0.85 | ALDH1A1 (0.45) | L3MBTL1MAPTCYP2C19ALDH1A1MEN1 | |
| SCHEMBL28519536 | 0.83 | USP2 (0.42) | MAPTALDH1A1USP2ENPP2LMNA | |
| SCHEMBL28529096 | 0.79 | NPC1 (0.42) | L3MBTL1MAPTHPGDALDH1A1MEN1 | |
| SCHEMBL28519499 | 0.77 | RXRA (0.40) | L3MBTL1MAPTALDH1A1NPSR1MAPK1 | |
| SCHEMBL28524257 | 0.74 | ENPP2 (0.46) | L3MBTL1MAPTCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL29954639 | 0.73 | ENPP2 (0.32) | L3MBTL1POLBENPP2TDP1 | |
| SCHEMBL28521411 | 0.73 | ENPP2 (0.51) | ALDH1A1NPSR1POLBMAPK1ENPP2 | |
| SCHEMBL28908256 | 0.71 | MRGPRX4 (0.41) | L3MBTL1MAPTHPGDCYP2C9CYP2C19 | |
| SCHEMBL28520513 | 0.70 | CA1 (0.41) | L3MBTL1MAPTCYP2C19ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108602834-B | Bruton's tyrosine kinase inhibitor | 北京盛诺基医药科技股份有限公司 | 2021-01-08 | — | — | CN | disclosed |