Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2061803 | 0.80 | SLC6A4 (0.43) | FDPSAKT1HDAC3HDAC1HDAC2 | |
| SCHEMBL7211228 | 0.80 | FDPS (0.37) | L3MBTL1FDPSAKT1HDAC3HDAC1 | |
| SCHEMBL27829838 | 0.78 | HDAC3 (0.37) | L3MBTL1FDPSAKT1HDAC3HDAC1 | |
| SCHEMBL5010708 | 0.76 | AAK1 (0.38) | FDPSAKT1HDAC3HDAC1HDAC2 | |
| SCHEMBL8605151 | 0.75 | HDAC3 (0.40) | L3MBTL1FDPSAKT1HDAC3HDAC1 | |
| SCHEMBL5271185 | 0.74 | MTNR1A (0.47) | L3MBTL1FDPSALDH1A1HSD17B10KDM4E | |
| SCHEMBL3406057 | 0.73 | HDAC3 (0.39) | AKT1HDAC3HDAC1HDAC2NCOR2 | |
| SCHEMBL23819882 | 0.72 | RIPK1 (0.47) | L3MBTL1HDAC1HDAC2ATMALDH1A1 | |
| SCHEMBL2728970 | 0.72 | L3MBTL1 (0.38) | L3MBTL1 | |
| SCHEMBL6677666 | 0.71 | ESR1 (0.42) | L3MBTL1AKT1HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108112251-B | NRF2 modulators | 葛兰素史克知识产权发展有限公司 | 2021-03-05 | — | — | CN | disclosed |