Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 2/20 | 0.41 |
| ▸ | PDE5A | O76074 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21094095 | 0.91 | FFAR2 (0.46) | FFAR2RIPK1STSPDE5AMAOA | |
| SCHEMBL20835651 | 0.89 | FFAR2 (0.56) | FFAR2RIPK1STSPDE5AMAOA | |
| SCHEMBL28534291 | 0.88 | GPR119 (0.44) | MAOAMAOBGRM5MAPTABCB1 | |
| SCHEMBL28523802 | 0.87 | RIPK1 (0.48) | FFAR2RIPK1PDE5AMAOAMAOB | |
| SCHEMBL28534271 | 0.86 | ABCB1 (0.44) | FFAR2RIPK1ABCB1 | |
| SCHEMBL28907091 | 0.85 | CNR1 (0.37) | FFAR2STSMAPTUSP30 | |
| SCHEMBL28527618 | 0.84 | RIPK1 (0.45) | FFAR2RIPK1STSPDE5AMAOA | |
| SCHEMBL21094084 | 0.84 | FFAR2 (0.42) | FFAR2RIPK1ABCB1 | |
| SCHEMBL2581106 | 0.84 | TP53 (0.44) | FFAR2RIPK1STSPDE5ATP53 | |
| SCHEMBL20835422 | 0.83 | FFAR2 (0.49) | FFAR2RIPK1PDE5AMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |