Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 3/20 | 0.44 |
| ▸ | TAS1R1 | Q7RTX1 | 3/20 | 0.44 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.42 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854219 | 0.94 | ALDH1A1 (0.47) | KMT2AMEN1MAPK1LMNASMN1; SMN2 | |
| SCHEMBL2857660 | 0.92 | LMNA (0.48) | KMT2AMEN1DHODHTAS1R3TAS1R1 | |
| SCHEMBL2860401 | 0.88 | MAPK13 (0.47) | TAS1R3TAS1R1MAPK1SMN1; SMN2ALDH1A1 | |
| SCHEMBL2856213 | 0.86 | CNR1 (0.47) | KMT2ATAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL2850250 | 0.77 | EPHX2 (0.43) | MAPK1LMNASMN1; SMN2ALDH1A1NPSR1 | |
| SCHEMBL2850487 | 0.76 | HTT (0.48) | KMT2AMEN1TAS1R3TAS1R1MAPK1 | |
| SCHEMBL3423831 | 0.76 | ALDH1A1 (0.55) | DHODHTAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL3390180 | 0.76 | ALDH1A1 (0.55) | DHODHTAS1R3TAS1R1TAS1R2LMNA | |
| SCHEMBL2850723 | 0.76 | TAOK3 (0.47) | KMT2AMEN1DHODHLMNASMN1; SMN2 | |
| SCHEMBL2854804 | 0.73 | MAPK1 (0.48) | MAPK1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |