Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.44 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854713 | 0.94 | NTRK1 (0.49) | HTTALDH1A1NTRK1MEN1KMT2A | |
| SCHEMBL2850723 | 0.93 | TAOK3 (0.47) | HTTALDH1A1SMN1; SMN2L3MBTL1CNR2 | |
| SCHEMBL2860851 | 0.88 | CNR1 (0.46) | HTTALDH1A1NTRK1SMN1; SMN2CNR1 | |
| SCHEMBL2854219 | 0.82 | ALDH1A1 (0.47) | HTTALDH1A1NTRK1SMN1; SMN2MEN1 | |
| SCHEMBL2857348 | 0.78 | SPR (0.54) | ALDH1A1NTRK1MAPK1TAS1R3TAS1R1 | |
| SCHEMBL2852199 | 0.76 | KMT2A (0.47) | HTTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2860401 | 0.76 | MAPK13 (0.47) | HTTALDH1A1NTRK1SMN1; SMN2MAPK1 | |
| SCHEMBL3395550 | 0.76 | SPR (0.55) | ALDH1A1CNR2TAS1R3TAS1R1 | |
| SCHEMBL2857660 | 0.76 | LMNA (0.48) | HTTALDH1A1SMN1; SMN2CNR1MEN1 | |
| SCHEMBL3391804 | 0.76 | SPR (0.55) | ALDH1A1CNR2TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |