Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | PDE2A | O00408 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2854219 | 0.94 | ALDH1A1 (0.47) | MAPTPOLBSMN1; SMN2NTRK1ALDH1A1 | |
| SCHEMBL2856213 | 0.92 | CNR1 (0.47) | MAPK13MAPK12MAPK11MAPK14POLB | |
| SCHEMBL2852199 | 0.88 | KMT2A (0.47) | SMN1; SMN2ALDH1A1HTTMAPK1TAS1R3 | |
| SCHEMBL2857660 | 0.87 | LMNA (0.48) | SMN1; SMN2ALDH1A1HTTMAPK1TAS1R3 | |
| SCHEMBL2854682 | 0.82 | ALDH1A1 (0.60) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2854713 | 0.82 | NTRK1 (0.49) | MAPK13MAPK12MAPK11MAPK14MAPT | |
| SCHEMBL2850487 | 0.76 | HTT (0.48) | SMN1; SMN2NTRK1ALDH1A1HTTMAPK1 | |
| SCHEMBL2850725 | 0.76 | MAPT (0.54) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2857566 | 0.75 | CNR1 (0.54) | MAPTPOLBSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL2860851 | 0.75 | CNR1 (0.46) | MAPK13MAPK12MAPK11MAPK14MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1451160-B1 | PYRAZOLE-AMIDES FOR USE IN THE TREATMENT OF PAIN | ICAGEN INC (US) | 2010-01-13 | — | — | EP | claimed |