Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 0.61 |
| ▸ | GRIN1 | Q05586 | 5/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25909811 | 0.78 | HSP90AA1 (0.41) | GRIN2B | |
| SCHEMBL18363279 | 0.76 | GRIN2B (1.00) | GRIN2BGRIN1KCNH2CYP2C9CYP2C19 | |
| SCHEMBL31194282 | 0.76 | GABRG2 (0.39) | GRIN2BGRIN1 | |
| SCHEMBL20483115 | 0.75 | KDM4E (0.39) | GRIN2B | |
| SCHEMBL18363208 | 0.74 | GRIN2B (1.00) | GRIN2BGRIN1KCNH2CYP2C9CYP2C19 | |
| SCHEMBL25229548 | 0.74 | ALDH1A1 (0.41) | — | |
| SCHEMBL31194316 | 0.74 | MET (0.43) | GRIN2BGRIN1 | |
| SCHEMBL20398324 | 0.74 | GRIN2B (0.73) | GRIN2BGRIN1KCNH2CYP2C9CYP2C19 | |
| SCHEMBL28523558 | 0.73 | GRIN2B (0.77) | GRIN2BGRIN1KCNH2CYP2C9CYP2C19 | |
| SCHEMBL18363435 | 0.72 | GRIN2B (1.00) | GRIN2BGRIN1KCNH2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108026094-B | Substituted 4-azaindoles and their use as modulators of the GLUN2B receptor | 詹森药业有限公司 | 2021-02-09 | — | — | CN | disclosed |